METHODS FOR INHIBITING FIBROSIS IN A SUBJECT IN NEED THEREOF

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20250092157A1
SERIAL NO

18793635

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Abstract

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In one aspect, the invention provides methods for treating, inhibiting, alleviating or preventing fibrosis in a mammalian subject suffering, or at risk of developing a disease or disorder caused or exacerbated by fibrosis and/or inflammation. In one embodiment, the invention provides methods of treating a subject suffering from renal fibrosis. In one embodiment, the invention provides methods of reducing proteinuria in a subject suffering from a renal disease or condition associated with proteinuria. The methods comprise the step of administering, to a subject in need thereof, an amount of a MASP-2 inhibitory agent effective to inhibit MASP-2-dependent complement activation.

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Patent Owner(s)

Patent OwnerAddress
UNIV LEICESTERLEICESTERSHIRE ENGLAND

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brunskill, Nigel John South Croxton, GB 8 29
Demopulos, Gregory A Mercer Island, US 169 2686
Dudler, Thomas Bellevue, US 55 395
Schwaeble, Hans-Wilhelm Mountsorrel, GB 76 652

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