ANTI-CDH6 ANTIBODIES AND ANTIBODY-DRUG CONJUGATES THEREOF
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United States of America
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Issued Date -
Mar 20, 2025
app pub date -
Dec 9, 2022
filing date -
Dec 9, 2022
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Abstract
Provided is an antigen-binding protein having the following properties: (a) specifically binding to CDH6, and (b) having the activity of being internalized into CDH6-expressing cells by binding to CDH6. Further provided an immunoconjugate comprising an antibody or antigen binding fragment thereof that specifically binds to CDH6 and has internalization activity, a pharmaceutical product comprising the immunoconjugate and having therapeutic effects on a tumor, a method for treating a tumor using the immunoconjugate or the pharmaceutical product, and the like.
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