THERAPEUTIC USE OF CANCER-ASSOCIATED FIBROBLAST-ENCAPSULATED PANCREATIC BETA CELLS FOR TREATING DIABETES
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United States of America
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Mar 20, 2025
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Sep 13, 2024
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Sep 13, 2024
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Abstract
Disclosed herein are compositions comprising one or more cell types encapsulated by a plurality of cancer-associated fibroblasts (CAFs) and/or fibroblasts; and/or one or more cell types encapsulated by extracellular matrix (ECM) secreted by CAFs and/or fibroblasts. Also disclosed are methods for producing compositions disclosed herein, methods of using compositions disclosed herein for treatment of diseases and/or disorders, and kits for practicing the methods disclosed herein.
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