5-FU AND RNAOG COMBINED IMMUNOCHEMOTHERAPY FOR PANCREATIC CANCER TREATMENT
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United States of America
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Mar 20, 2025
app pub date -
Jan 10, 2023
filing date -
Jan 10, 2023
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Abstract
Described herein are compositions comprising RNA origami (RNAOG) which include 5-fluorouracil (5FU) or analogues thereof are described which can be used to both directly treat a cancer by inhibiting a biochemical pathway overexpressed in a cancer cell and indirectly treat a cancer by inducing an anti-cancer immune response. Also described herein are methods of using said compositions for treating cancer, inducing an anti-cancer immune response, and/or killing a cancer cell.
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