METHODS OF TREATING DISORDERS ASSOCIATED WITH CASTOR
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United States of America
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Mar 20, 2025
app pub date -
Apr 22, 2024
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Apr 22, 2024
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Abstract
The present disclosure relates to methods of treating a coenzyme A reduction, elevation, sequestration, toxicity, or redistribution (CASTOR) disease such as, for example, defects in fatty acid oxidation enzymes, methylmalonic acidemia, glutaric acidemia, propionic academia, and HMG-CoA lyase, via small molecule modulators of CoA levels. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.
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