MARKER, KIT AND METHOD FOR ANALYSING A BIOLOGICAL SAMPLE
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United States of America
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Mar 6, 2025
app pub date -
Sep 4, 2024
filing date -
Sep 4, 2024
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Abstract
A marker for analysing a biological sample includes an affinity reagent with a backbone and a barcode oligonucleotide attached to the backbone. The backbone is configured to specifically bind to a target analyte. The marker further includes a label comprising a label oligonucleotide and at least one labelling moiety. The label oligonucleotide and the barcode oligonucleotide of the affinity reagent are configured to hybridise to each other. One of the label oligonucleotide and the barcode oligonucleotide is sensitive to a degradation agent. The other one of the label oligonucleotide and the barcode oligonucleotide is resistant to the degradation agent.
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