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Abstract

Sterilizable enzymatic sensors and sensor assemblies are provided, the enzymatic sensor including at least one enzymatic sensing membrane located at or near a distal tip of the enzymatic sensor. A sensor assembly may be packaged in a partially assembled state within a flexible package, at least a portion of which is permeable to ethylene oxide (ETO). The sensor assembly may also include a flexible tube which can be connected to the enzymatic sensor such that a distal section of the enzymatic sensor is positioned within an interior of the flexible tube, and a distal tube cap connected to a distal end of the flexible tube, the cap including an internal passage allowing passage of the distal tip of the enzymatic sensor therethrough, a plurality of filtered ports, and a gasket dimensioned to form a fluid-tight seal when a portion of the sensor is inserted through the gasket. The sensor assembly may also include a sealing membrane to occlude a distal end of the internal passage of the distal tube cap. Further assembly of the sensor assembly may be performed within the flexible package after ETO sterilization.

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First Claim