HYALURONIC ACID DERIVATIVE OR SALT THEREOF, AND PREPARATION METHOD THEREFOR AND APPLICATION THEREOF

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United States of America

APP PUB NO 20250075009A1
SERIAL NO

18727479

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Abstract

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A hyaluronic acid derivative or a salt thereof, and a preparation method therefor and an application thereof. Hyaluronic acid is used as a matrix skeleton, and a methoxypolyethylene glycol epoxy derivative is used to modify hyaluronic acid to prepare a pegylated hyaluronic acid derivative. The skeleton of hyaluronic acid is wound by using polyethylene glycol linear macromolecules, so that a glycosidic bond facilitating enzymolysis is masked, a circulation duration of sodium hyaluronate in the body is prolonged, and the moisture retention and moisture lock effect can be better exerted. Meanwhile, polyethylene glycol and sodium hyaluronate, serving as artificially synthesized and naturally existing high polymer materials, both have good biocompatibility and biodegradability, and are combined, so that the advantages of the high polymer material can be better exerted.

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Patent Owner(s)

Patent OwnerAddress
JENKEM TECHNOLOGY CO LTD (TIANJIN)NO 9 KANGCHENG STREET WEST ZONE OF TEDA DEVELOPMENT ZONE TIANJIN 300462

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHEN, Xiaomeng Tianjin, CN 121 2120
LIN, Meina Tianjin, CN 33 54
SUN, Yu Tianjin, CN 426 3781
ZHAO, Xuan Tianjin, CN 202 3301

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