PHARMACEUTICAL COMPOSITION FOR TREATING PERIPHERAL NERVE INJURY

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United States of America

APP PUB NO 20250074976A1
SERIAL NO

18293199

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Abstract

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A pharmaceutical composition for treating peripheral nerve injury, includes a substance that inhibits the formation of neutrophil extracellular traps (NETs) outside the parenchyma of injured peripheral nerves, for example, a substance that inhibits the accumulation of neutrophils in injured peripheral nerves, a substance that suppresses the expression or inhibits the function of macrophage migration inhibitory factor (MIF), etc. Further provided is a method for evaluating the peripheral nerve regeneration-promoting activity of a test substance using, as an indicator, the activity to inhibit the formation of NETs outside the parenchyma of injured peripheral nerves, for example, the activity to inhibit the accumulation of neutrophils in injured peripheral nerves, the activity to suppress the expression of MIF or the activity to inhibit the function thereof, etc.

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Patent Owner(s)

Patent OwnerAddress
NATIONAL UNIVERSITY CORPORATION HOKKAIDO UNIVERSITYKITA 8-JYO NISHI 5-CHOME KITA-KU SAPPORO-SHI HOKKAIDO 0600808 ?0600808

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
KADOYA, Ken Sapporo-shi, JP 2 0
YAMAMOTO, Yasuhiro Sapporo-shi, JP 329 2897

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