Importance

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Abstract

Devices and methods for treating a skin of a patient using a serum comprising a plurality of microbubbles and a plurality of active elements are disclosed herein. The system can comprise a handpiece comprising a proximal end and a distal end; a distal tip at the distal end of the handpiece, the distal tip configured to deliver the serum; an ultrasonic transducer in the distal tip; and an inflow port in the distal tip in fluid communication with a source configured to hold the serum, where the inflow port is configured for topical application to the skin; wherein application of acoustic energy from the ultrasonic transducer causes the plurality of microbubbles in the serum delivered to the skin to oscillate causing cavitation of the plurality of microbubbles causing permeabilization of the skin allowing for penetration of the plurality of active elements in the serum to penetrate the skin.

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First Claim