CANCER VACCINES TARGETING BORIS AND USES THEREOF
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United States of America
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Issued Date -
Feb 20, 2025
app pub date -
Nov 1, 2024
filing date -
Nov 1, 2024
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Abstract
Disclosed herein are nucleic acid molecules comprising one or more nucleic acid sequences that encode a synthetic consensus BORIS antigen. Vectors, compositions, and vaccines comprising one or more nucleic acid sequences that encode a synthetic consensus BORIS antigen are disclosed. Methods of treating a subject with a BORIS-expressing tumor and methods of preventing a BORIS-expressing tumor are disclosed. A synthetic consensus BORIS antigen is disclosed.
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