ANTIBODY-DRUG CONJUGATE
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United States of America
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Issued Date -
Feb 13, 2025
app pub date -
Sep 19, 2024
filing date -
Sep 19, 2024
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Abstract
As an antitumor drug which is excellent in terms of antitumor effect and safety, there is provided an antibodydrug conjugate in which an antitumor compound represented by the following formula is conjugated to an antibody via a linker having a structure represented by the following formula: -L1-L2-LP-NH—(CH2)n1-La-Lb-Lc- wherein the antibody is connected to the terminal of L1, and the antitumor compound is connected to the terminal of Lc with the nitrogen atom of the amino group at position 1 as a connecting position.
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