Substrates and Optical Systems and Methods of Use Thereof
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United States of America
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Feb 6, 2025
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Jul 16, 2024
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Jul 16, 2024
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Abstract
This invention provides analytical devices for use in various applications, including detection of single-molecule analytical reactions. Methods for propagating optical energy within a substrate are provided. Devices comprising waveguide substrates, dielectric omnidirectional reflectors, and optical couplers are provided. Waveguide substrates with improved uniformity of optical energy intensity across one or more waveguides and enhanced waveguide illumination efficiency within an analytic detection region of the arrays are provided.
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