METHOD FOR DETECTING MUTATION IN TARGET BASE SEQUENCE OF NUCLEIC ACID, METHOD FOR SELECTIVELY INHIBITING AMPLIFICATION OF NUCLEIC ACID, AND KITS FOR PERFORMING SAME
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United States of America
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Issued Date -
Feb 6, 2025
app pub date -
Dec 1, 2022
filing date -
Dec 1, 2022
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Abstract
One purpose of the present invention is to provide a simple method by which a mutant gene can be detected at a lower mutant gene content than the mutant gene detection limit by the ordinary clamp-PCR method, and a kit for performing the method. Another purpose of the present invention is to provide a simple method by which, in a nucleic acid amplification reaction, the amplification of a target base sequence can be selectively inhibited, and a kit for performing the method. In a nucleic acid amplification reaction, a diallylamine/sulfur dioxide copolymer or an acid addition salt thereof comprising a constituent unit (A) having a structure represented by general formula (I-a) or (I-b):
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