Mammalian ATG8 Proteins and ATG9A Direct Sealing of Autophagosomal Membranes

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20250043285A1
SERIAL NO

18761527

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Abstract

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The present invention relates to discovery that modulators of ATG8 and/or ATG9A act in sequence to orchestrate the sealing of autophagosomal membranes. The present invention is directed to use of these agents and this mechanism in the treatment of various disease states and/or conditions, especially cancer.

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Patent Owner(s)

Patent OwnerAddress
UNM RAINFOREST INNOVATIONSALBUQUERQUE NM

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Deretic, Vojo Placitas, US 9 44
Javed, Rujeena Albuquerque, US 1 0
Timmins, Graham Albuquerque, US 28 40

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