SERPINA1 iRNA COMPOSITIONS AND METHODS OF USE THEREOF

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20250043279A1
SERIAL NO

18644183

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Abstract

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The invention relates to RNAi agents, e.g., double stranded RNAi agents, targeting the Serpina1 gene, and methods of using such RNAi agents to inhibit expression of Serpina1 and methods of treating subjects having a Serpina1 associated disease, such as a liver disorder.

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Patent Owner(s)

Patent OwnerAddress
ALNYLAM PHARMACEUTICALS INC675 WEST KENDALL STREET HENRI A TERMEER SQUARE CAMBRIDGE MA 02142

International Classification(s)

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brown, Christopher Cambridge, US 259 3110
Charisse, Klaus Acton, US 73 449
Fitzgerald, Kevin Brookline, US 209 2389
Foster, Donald Attleboro, US 35 131
Jadhav, Vasant R Sharon, US 43 88
Janas, Maja Cambridge, US 8 16
Jayaraman, Muthusamy Cambridge, US 107 3970
Kel'in, Alexander V Swampscott, US 15 14
Maier, Martin A Belmont, US 82 746
Manoharan, Muthiah Weston, US 491 18658
Matsuda, Shigeo Cambridge, US 47 578
Milstein, Stuart Arlington, US 133 755
Nair, Jayaprakash K Cambridge, US 63 214
Rajeev, Kallanthottathil G Wayland, US 260 8660
Schlegel, Mark K Boston, US 71 33
Sehgal, Alfica Medford, US 46 123

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