SOS1 Inhibitor With Pyrido-Fused Six-Membered Ring Structure

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20250042857A1
SERIAL NO

18695940

Stats

ATTORNEY / AGENT: (SPONSORED)

Importance

Loading Importance Indicators... loading....

Abstract

See full text

The present invention relates to an SOS1 inhibitor with a pyrido-fused-six-membered ring structure, a preparation method therefor, and use thereof. The SOS1 inhibitor has the structural formula shown in formula (I) and an inhibitory activity on SOS1, and can be used to treat head and neck cancer, lung cancer, a mediastinal tumor, a gastrointestinal tumor, prostate cancer, testicular cancer, a gynecological tumor, breast cancer, renal and bladder cancer, an endocrine tumor, soft tissue sarcoma, osteosarcoma, rhabdomyosarcoma, mesothelioma, skin cancer, a peripheral nerve tumor, a central nervous system tumor, lymphoma, leukemia, Noonan syndrome, cardio-facio-cutaneous syndrome, and hereditary gingival fibromatosis and a related syndrome thereof.

Loading the Abstract Image... loading....

First Claim

See full text

Family

Loading Family data... loading....

Patent Owner(s)

  • HAIHE BIOPHARMA CO., LTD.

International Classification(s)

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CAI, Yalei Shanghai, CN 2 0
GAO, Shanyun Shanghai, CN 3 0
LI, Dongsheng Shanghai, CN 160 442
LI, Leping Shanghai, CN 119 2017
LIU, Cailu Shanghai, CN 1 0
TU, Wangyang Shanghai, CN 8 11
XIE, Qing Shanghai, CN 56 1135
YANG, Maozhi Shanghai, CN 2 0
YU, Bing Shanghai, CN 323 612
ZHANG, Yixiang Shanghai, CN 22 37

Cited Art Landscape

Load Citation

Patent Citation Ranking

Forward Cite Landscape

Load Citation