HUMAN ALPHA-GALACTOSIDASE VARIANTS

United States of America

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Issued Date
Feb 6, 2025
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May 6, 2024
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May 6, 2024

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Abstract

The present invention provides engineered human alpha-galactosidase polypeptides and compositions thereof. The engineered human alpha-galactosidase polypeptides have been optimized to provide improved stability under both acidic (pH<4.5) and basic (pH>7) conditions. The invention also relates to the use of the compositions comprising the engineered human alpha-galactosidase polypeptides for therapeutic purposes.

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CROSSWALK THERAPEUTICS INC	790 MEMORIAL DRIVE SUITE 302 CAMBRIDGE MA 02319

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Inventor Name	Address	# of filed Patents	Total Citations
Agard, Nicholas J	San Francisco, US	62	532
Huisman, Gjalt W	Redwood City, US	150	2275
Miller, Mathew G	San Carlos, US	24	52
Zhang, Xiyun	Fremont, US	141	584

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HUMAN ALPHA-GALACTOSIDASE VARIANTS

Number of patents in Portfolio can not be more than 2000

United States of America

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