A METHOD FOR DETECTING CLUSTERING OF RAS PROTEIN

Number of patents in Portfolio can not be more than 2000

United States of America

APP PUB NO 20250035634A1
SERIAL NO

18717849

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present invention relates to a method of detecting clustering of Rat Sarcoma Vims (Ras) protein in a cell comprising culturing the cells on an array of nanostructures and detecting the clustering of Ras protein around the nanostructures by using optical microscopy. In one embodiment, the nanostructures are nanobars. The invention further relates to the use of the method in identifying the isoform or mutation status of Ras protein, and anti-Ras drug screening.

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Patent Owner(s)

  • NANYANG TECHNOLOGICAL UNIVERSITY; UNIVERSITY MEDICAL CENTER OF THE JOHANNES GUTENBERG UNIVERSITY MAINZ

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
JALINGAM, Krishnaraj Mainz, DE 1 0
MU, Huanwen Singapore, SG 1 0
ZHAO, Wenting Singapore, SG 7 6

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