METHOD OF PRODUCING HYDROXYPROPYL METHYLCELLULOSE ACETATE SUCCINATE POWDER
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United States of America
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Jan 30, 2025
app pub date -
Jul 25, 2024
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Jul 25, 2024
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Provided is a method of producing an esterified cellulose ether having improved flowability of the powder, where the method can reduce production of fine powder in the precipitated esterified cellulose ether. The method is a method of producing hydroxypropyl methylcellulose acetate succinate powder which essentially includes an esterification reaction step, a precipitation step, a washing/recovering step and a drying step, wherein the precipitation step is a step of extruding the reaction solution, prepared in the esterification reaction step, into water from extruding ports of an extruder to form a precipitate, and then mincing the resultant precipitate to obtain a suspension containing hydroxypropyl methylcellulose acetate succinate particles.
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