OPTIMIZED ANTIBODY VARIABLE REGIONS
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United States of America
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Issued Date -
Jan 30, 2025
app pub date -
Sep 13, 2024
filing date -
Sep 13, 2024
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Abstract
The present invention is directed to optimized anti-CD3 variable sequences for use in a variety of bispecific formats, including those that utilize scFv components. The invention further relates to nucleic acids encoding for the polypeptide, to vectors comprising the same and to host cells comprising the vector. In another aspect, the invention provides for a pharmaceutical composition comprising the mentioned polypeptide and medical uses of the polypeptide.
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