DLL3 TARGETING PEPTIDES AND CONSTRUCTS THEREOF
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United States of America
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Jan 30, 2025
app pub date -
Jun 13, 2024
filing date -
Jun 13, 2024
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Abstract
The present disclosure relates to targeting moieties such as peptides and antibodies that can bind to DLL3. The disclosure also provides targeting constructs, which may include a targeting moiety attached, via an optional linker, to a chelating agent for association of a cargo. Methods of making the constructs and formulations thereof are also provided. Methods of using the constructs and/or formulations thereof to treat subjects, for example, to treat or prevent cancer, are also described.
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