NEW CRYSTAL FORM OF ERTAPENEM SODIUM AND PREPARATION METHOD THEREFOR
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United States of America
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Jan 30, 2025
app pub date -
Dec 1, 2021
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Dec 1, 2021
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Abstract
The disclosure provides a new crystal form of ertapenem sodium and preparation method therefor. The new crystal form of ertapenem sodium has 27 principal characteristic peaks in an X-ray powder diffraction diagram. The crystal form of ertapenem sodium of the disclosure has a rod-like crystal habit, which has a large particle size, is not prone to aggregation and is easier to dry, and a product with high crystallinity and high purity may be obtained by simple drying treatment. Meanwhile, the crystal form of the disclosure has better stability, and the crystal form may remain unchanged to a maximum extent in subsequent washing and drying processes, thereby further improving the purity of the product.
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