CRISPR-MEDIATED TRANSGENE INSERTION IN NEONATAL CELLS
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United States of America
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Issued Date -
Jan 30, 2025
app pub date -
Feb 2, 2023
filing date -
Feb 2, 2023
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Abstract
Compositions and methods for inserting a nucleic acid encoding a polypeptide of interest into a target genomic locus in a neonatal cell, a population of neonatal cells, or a neonatal subject or for expressing a nucleic acid encoding a polypeptide of interest in a neonatal cell, a population of neonatal cells, or a neonatal subject are provided. Also provided are neonatal cells or populations of neonatal cells comprising a nucleic acid construct comprising a coding sequence for a polypeptide of interest inserted into a target genomic locus.
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