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Patent Owner(s)

Patent Owner	Address
GENZYME CORPORATION	450 WATER STREET CAMBRIDGE MA 02141

International Classification(s)

• C12N:MICRO-ORGANISMS OR ENZYMES; COMPOSITIONS THEREOF
• G01N:INVESTIGATING OR ANALYSING MATERIALS BY DETERMININ....

Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
JIN, Xiaoying	Cambridge, US	15	30
# of filed Patents : 15 Total Citations : 30
Liu, Lin	Cambridge, US	241	2041
# of filed Patents : 241 Total Citations : 2041
O'Riordan, Catherine	Cambridge, US	20	159
# of filed Patents : 20 Total Citations : 159
Zhang, Kate	Cambridge, US	4	7
# of filed Patents : 4 Total Citations : 7

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Full Text

US Patent Application No: 2025/0027,951

METHODS FOR DETECTING AAV

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Abstract

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Provided herein are methods for determining the serotype of a virus particle and/or or determining the heterogeneity of a virus particle (e.g., an AAV particle). In other embodiments, the invention provides methods to determine the heterogeneity of AAV particles. In some aspects, the invention provides viral particles (e.g., rAAV particles) with improved stability and/or improved transduction efficiency by increasing the acetylation and/or deamidation of capsid proteins.

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Description

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