ACTIVATING APPENDAGES TO INDUCE POLYPHARMACOLOGY IN PEPTIDE HORMONE ANALOGUES, INCLUDING DUAL GLP-1R / GIP AGONISM

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United States of America Patent

APP PUB NO 20250026782A1
SERIAL NO

18752309

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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Compounds, method of making the compounds, and methods of using the compounds to treat Type 2 diabetes and obesity in mammals, including humans. The compounds are dual GLP-1 receptor and GIP receptor agonists in which at least one side chain of a residue in GLP-1 and/or GIP is modified such that the modified GLP-1 and GIP are agonists of both GLP-1 receptor and GIP receptor.

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Patent Owner(s)

Patent OwnerAddress
WISCONSIN ALUMNI RESEARCH FOUNDATION614 WALNUT STREET MADISON WI 53726

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  • 2024 Application Filing Year
  • A61K Class
  • 9279 Applications Filed
  • 536 Patents Issued To-Date
  • 5.78 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Brown, Kyle Alexander Queens, US 1 0
Gellman, Samuel Helmer Madison, US 17 60
Morris, Rylie Kathleen Madison, US 1 0

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges9747201 - 1005001000150020002500300035004000450050005500600065007000750080008500900095001000010500

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