ENGINEERED SAFETY IN CELL THERAPY

United States of America Patent

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Issued Date
Jan 23, 2025
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Aug 29, 2024
filing date
Aug 29, 2024

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Abstract

The present disclosure relates to compositions and methods for treating cancer. For example, a modified cell may include a polynucleotide comprising an NFAT promoter, a nucleotide sequence encoding therapeutic agent, and a nucleotide sequence encoding a VHL-interaction domain of HIF1α, wherein the therapeutic agent comprises, for example, IL-12, IL-6, and/or IFNγ.

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Patent Owner(s)

Patent Owner	Address
INNOVATIVE CELLULAR THERAPEUTICS HOLDINGS LTD	190 ELGIN AVENUE GEORGE TOWN KY1-9008
INNOVATIVE CELLULAR THERAPEUTICS INC	1405 RESEARCH BOULEVARD SUITE 210 ROCKVILLE MD 20850

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Inventor(s)

Inventor Name	Address	# of filed Patents	Total Citations
Cao, Zhiyuan	Rockville, US	51	224
Pu, Chengfei	Shanghai, CN	53	220
Wu, Zhao	Rockville, US	109	362
Xiao, Lei	Rockville, US	199	885

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ENGINEERED SAFETY IN CELL THERAPY

Number of patents in Portfolio can not be more than 2000

United States of America Patent

18819922

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18819922

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Abstract

First Claim

Family

Patent Owner(s)

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