MUTANT PROTEASES AND USES THEREOF
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United States of America
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Jan 16, 2025
app pub date -
Oct 26, 2021
filing date -
Oct 26, 2021
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Abstract
The present disclosure, in some aspects, provides mutant TEV proteases that exhibit improved activity, where the mutant TEV exhibits increase efficiency and/or an increased Kcat for cleavage of an amino acid sequence, and TEV proteases are commonly used for laboratory methods including cleaving fusion proteins and removing a purification tag, such as a maltose binding protein or a poly-histidine tag, from a fusion protein or an antibody.
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