COMPOSITIONS AND METHODS FOR HEMATOPOIETIC STEM CELL TRANSPLANTS
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United States of America
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Jan 16, 2025
app pub date -
Jun 14, 2024
filing date -
Jun 14, 2024
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Abstract
The present disclosure provides distinct therapeutic populations of cells that form a pharmaceutical composition useful in hematopoietic stem/progenitor cell transplant. For example, the present disclosure provides a therapeutic population of cells, comprising an enriched population of hematopoietic stem/progenitor cells, memory T cells, regulatory T cells, and wherein the population of cells is depleted of naïve conventional αβ-T cells. The present disclosure further provides methods of treatment using the therapeutic population of cells. In other embodiments, the present disclosure provides methods of producing a therapeutic population of cells.
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