BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS
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United States of America
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Issued Date -
Jan 16, 2025
app pub date -
Jul 2, 2024
filing date -
Jul 2, 2024
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Abstract
The invention relates to 1,5-benzothiazepine and 1,2,5-benzothiadiazepine derivatives of formula (I). These compounds are bile acid modulators having apical sodium-dependent bile acid transporter (ASBT) and/or liver bile acid transport (LBAT) inhibitory activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment of cardiovascular diseases, fatty acid metabolism and glucose utilization disorders, gastrointestinal diseases and liver diseases.
First Claim
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Family

- 15 United States
- 10 France
- 8 Japan
- 7 China
- 5 Korea
- 2 Other
Patent Owner(s)
Patent Owner | Address | |
---|---|---|
ALBIREO AB | GÖTEBORG |
International Classification(s)

- 2024 Application Filing Year
- A61K Class
- 9279 Applications Filed
- 536 Patents Issued To-Date
- 5.78 % Issued To-Date
Inventor(s)
Inventor Name | Address | # of filed Patents | Total Citations |
---|---|---|---|
Gillberg, Per-Göran | Åsbro, SE | 69 | 1949 |
# of filed Patents : 69 Total Citations : 1949 | |||
Kulkarni, Santosh S | Bangalore, IN | 48 | 762 |
# of filed Patents : 48 Total Citations : 762 | |||
Starke, Ingemar | Göteborg, SE | 78 | 2308 |
# of filed Patents : 78 Total Citations : 2308 |
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- 0 Citation Count
- A61K Class
- 0 % this patent is cited more than
- < 1 Age
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