BENZOTHIA(DI)AZEPINE COMPOUNDS AND THEIR USE AS BILE ACID MODULATORS

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United States of America

APP PUB NO 20250019353A1
SERIAL NO

18762343

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The invention relates to 1,5-benzothiazepine and 1,2,5-benzothiadiazepine derivatives of formula (I). These compounds are bile acid modulators having apical sodium-dependent bile acid transporter (ASBT) and/or liver bile acid transport (LBAT) inhibitory activity. The invention also relates to pharmaceutical compositions comprising these compounds and to the use of these compounds in the treatment of cardiovascular diseases, fatty acid metabolism and glucose utilization disorders, gastrointestinal diseases and liver diseases.

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Patent Owner(s)

Patent OwnerAddress
ALBIREO ABGÖTEBORG

International Classification(s)

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  • 2024 Application Filing Year
  • A61K Class
  • 9279 Applications Filed
  • 536 Patents Issued To-Date
  • 5.78 % Issued To-Date
Click to zoom InYear of Issuance% of Matters IssuedCumulative IssuancesYearly Issuances202420250255075100

Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Gillberg, Per-Göran Åsbro, SE 69 1949
Kulkarni, Santosh S Bangalore, IN 48 762
Starke, Ingemar Göteborg, SE 78 2308

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Citation count rangeNumber of patents cited in rangeNumber of patents cited in various citation count ranges9747201 - 1005001000150020002500300035004000450050005500600065007000750080008500900095001000010500

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