PROCESS OF PURIFICATION OF PROTEIN
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United States of America
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Issued Date -
Jan 9, 2025
app pub date -
Sep 23, 2024
filing date -
Sep 23, 2024
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Abstract
The invention provides a process of purification of antibody or fusion protein from protein mixture comprising product and process related impurities. The process provides the use of hydroxyapatite chromatography for the separation of low molecular weight impurities and basic variants. In addition, invention further provides a scalable purification process to remove product and process related impurities.
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