MICRONEEDLE PATCH DEVICE WITH INTEGRATED BIOELECTRODE
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United States of America
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Issued Date -
Jan 9, 2025
app pub date -
Jul 5, 2024
filing date -
Jul 5, 2024
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Abstract
A device for transdermal electrochemical measurements, comprising a polymeric support having a surface provided for contact with skin, an array of polymeric microneedles integral with the support and projecting outward from the surface of the support, and a porous and/or nano/micro-structured bioelectrode. A biologically active species is immobilized on the surface of a conductive material. The microneedles and a surface of contact of the support with the skin are formed of a biocompatible crosslinked hydrogel, non-electron-conductive in the dry state and electrolyte-conductive upon contact with an aqueous fluid. The bioelectrode is arranged in contact with the hydrogel and is free of direct contact with the skin. Methods for preparing and using the device are also described.
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