METHOD AND APPARATUS USING COMPUTATIONAL PATHOLOGY FOR RISK STRATIFICATION OF CANCER

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United States of America

APP PUB NO 20240428906A1
SERIAL NO

18651738

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Abstract

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The present disclosure relate to a method. The method includes accessing segmented digitized pathology imaging data from a cancer patient. The segmented digitized pathology imaging data identifies segmented nuclei, segmented mitosis, and segmented tubule regions. A plurality of nuclear features are extracted using the segmented nuclei. A plurality of mitosis features are extracted using the segmented mitosis. A plurality of tubule features are extracted using the segmented tubule regions. A risk score is generated by operating a machine learning model on the plurality of nuclear features, the plurality of mitosis features, and the plurality of tubule features. The risk score correlates to a risk of recurrence of cancer for the cancer patient.

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CASE WESTERN RESERVE UNIVERSITY10900 EUCLID AVENUE CLEVELAND OH 44106

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Chen, Yuli Xi'an, CN 11 106
Li, Haojia Cleveland, US 4 0
Madabhushi, Anant Decatur, US 125 1412

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