METHODS FOR TREATING CELLULAR INFLAMMATION INDUCED BY AFB1
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United States of America
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Dec 26, 2024
app pub date -
Jun 20, 2024
filing date -
Jun 20, 2024
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Abstract
Embodiments of the present disclosure provide a method for treating cellular inflammation induced by AFB1, comprising administering to a patient an agent that increases a content or an expression level of miR-9, wherein the agent that increases the content or the expression level of miR-9 is miR-9 mimics or an expression vector containing miR-9, a nucleotide sequence of the miR-9 mimics is shown in SEQ ID No. 5 and a SEQ ID No. 6, and a nucleotide sequence of the miR-9 is shown in SEQ ID No. 5. The present disclosure increases the content or the expression level of miR-9 to antagonize an upstream signaling, block an occurrence of inflammatory response, and inhibit a pro-inflammatory effect of AFB1 on glomerular podocyte.
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