Terpolymers for Lipid Nanodisc Formation
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United States of America
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Dec 26, 2024
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Dec 14, 2022
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Dec 14, 2022
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Abstract
Terpolymers comprising optionally at least partially substituted styrene repeat units, N-alkylmaleimide repeat units and repeat units selected from the group consisting of maleic anhydride repeat units, maleic acid repeat units or maleic anhydride derivative repeat units and having a narrow molecular weight distribution are provided. The terpolymers may be used to solubilize lipid bilayers to form lipid nanodiscs and isolate membrane proteins.
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