BACTERIOPHAGE-DERIVED NANOPORE SENSORS
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United States of America
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Dec 26, 2024
app pub date -
May 13, 2024
filing date -
May 13, 2024
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Abstract
Disclosed herein are compositions and methods that involve inserting connector protein channels of bacteriophage DNA packaging motors into copolymeric membranes via liposome-polymer fusion, which can be used as nanopore sensors for biomedical applications such as high throughput protein sequencing or cancer diagnosis. For example, disclosed are compositions comprising a copolymeric membrane into which a connector protein channel of a bacteriophage packaging motor has been inserted.
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