METHOD FOR CROSSLINKING HYALURONIC ACID USING RESONANT ACOUSTIC MIXING
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United States of America
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Dec 19, 2024
app pub date -
Mar 29, 2023
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Mar 29, 2023
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Abstract
A process for crosslinking a polymer using resonant acoustic mixing is disclosed herein. The process comprises adding an aqueous solution comprising a dissolved base to the polymer to produce a substantially homogenous gel; adding a crosslinking agent to the substantially homogeneous gel to produce a mixture; and subjecting the mixture to resonant acoustic mixing conditions sufficient to effect crosslinking of the polymer, wherein the resonant acoustic mixing conditions comprise a forcing energy ranging between about 20 g to about 100 g. Also disclosed are cosmetic, therapeutic and/or prophylactic applications of products comprising a crosslinked polymer produced by resonant acoustic mixing.
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