CALICHEAMICIN DERIVATIVES AND ANTIBODY DRUG CONJUGATES THEREOF
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United States of America
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Dec 12, 2024
app pub date -
Apr 5, 2024
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Apr 5, 2024
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Abstract
The present invention is directed to novel calicheamicin derivatives useful as payloads in antibody-drug-conjugates (ADC's), and to payload-linker compounds and ADC compounds comprising the same; to pharmaceutical compositions comprising the same and to methods for using the same to treat pathological conditions such as cancer.
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