SOLID FORMS OF 3-((1R,3R)-1-(2,6-DIFLUORO-4-((1-(3-FLUOROPROPYL)AZETIDIN-3-YL)AMINO)PHENYL)-3-METHYL-1,3,4,9-TETRAHYDRO-2H-PYRIDO[3,4-B]INDOL-2-YL)-2,2-DIFLUOROPROPAN-1-OL AND PROCESSES FOR PREPARING FUSED TRICYCLIC COMPOUNDS COMPRISING A SUBSTITUTED PHENYL OR PYRIDINYL MOIETY, INCLUDING METHODS OF THEIR USE

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United States of America

APP PUB NO 20240409535A1
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18652953

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Abstract

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Provided herein are solid forms, salts, and formulations of 3-((1R,3R)-1-(2,6-difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol, processes and synthesis thereof, and methods of their use in the treatment of cancer.

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GENENTECH INCSOUTH SAN FRANCISCO CA

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
CHAKRAVARTY, Paroma SOUTH SAN FRANCISCO, US 10 14
CHUNG, Cheol Keun SOUTH SAN FRANCISCO, US 6 22
CLAGG, Kyle SAN FRANCISCO, US 4 5
DALZIEL, Michael CHICAGO, US 4 5
FETTES, Alec BASEL, CH 22 14
GOSSELIN, Francis SAN MATEO, US 59 271
IDING, Hans MAGDEN, CH 39 89
LIM, Ngiap-Kie DUBLIN, US 16 16
MCCLORY, Andrew SOUTH SAN FRANCISCO, US 9 6
NAGAPUDI, Karthik SOUTH SAN FRANCISCO, US 23 1337
ROBINSON, Sarah SOUTH SAN FRANCISCO, US 6 8
XU, Jie SAN MATEO, US 345 2150
ZHANG, Haiming SAN MATEO, US 57 133

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