Liquid aspiration with volume compensation
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United States of America
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Issued Date -
Dec 5, 2024
app pub date -
Jun 4, 2024
filing date -
Jun 4, 2024
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Abstract
A method for aspirating a liquid with a laboratory automation device comprises: lowering a pipette of the laboratory automation device into a vessel containing the liquid; during lowering, generating an underpressure or overpressure in the pipette with a pressure generating device of the laboratory automation device and measuring a pressure in a pressure distribution system interconnecting the pressure generating device with the pipette; detecting a liquid surface of the liquid in the vessel by evaluating a pressure change of the pressure; calculating a compensation volume from compartment volumes of compartments of the pressure distribution system and/or of the pipette and from pressure losses between the compartments; and aspirating the liquid from the vessel into the pipette by controlling the pressure generating device to aspirate a specific volume altered by the compensation volume.
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