METHOD FOR PRODUCING 2-HETEROARYLPYRIDINE COMPOUND
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United States of America
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Issued Date -
Nov 28, 2024
app pub date -
Nov 16, 2022
filing date -
Nov 16, 2022
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Abstract
The present invention provides a method for producing a compound represented by formula (3) (in the formula, Q, R1 and R2 are the same as those in formula (1) and formula (2)), comprising chemically reacting a compound represented by formula (1) (in the formula, Q represents a substituted or unsubstituted 5- to 6-membered or 9- to 10-membered heteroaryl group, and R1 represents a C1-6 alkyl group) with a compound represented by formula (2) (in the formula, R2 represents a hydrogen atom, a substituted or unsubstituted C1-6 alkyl group, a substituted or unsubstituted C3-6 cycloalkyl group, a substituted or unsubstituted phenyl group, or a substituted or unsubstituted 5- to 6-membered heteroaryl group) in the presence of a metal alkoxide or a base, and a method for producing a compound represented by formula (4) (in the formula, Q, R1 and R2 are the same as those in formula (3)), comprising chemically reacting the compound represented by formula (3) with a hydroxylamine or a salt thereof, and subjecting a product of the chemical reaction to a dehydration reaction,
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