PURIFICATION METHOD OF ANTIBODY COMPOSITION
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United States of America
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Issued Date -
Nov 21, 2024
app pub date -
May 6, 2022
filing date -
May 6, 2022
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Abstract
The present invention aims to provide a method for removing glycosylation isomers in antibody drugs, etc. The present invention provides, for example, a purification method for an antibody composition, said method comprising: loading the antibody composition on conventional chromatography to allow an antibody having no sugar chains attached to sites other than the Fc region glycosylation consensus region to be adsorbed to a media of the chromatography; and treating the media with an eluent to thereby elute the antibody adsorbed to the media to obtain a purified antibody composition.
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