SYNTHESIS AND APPLICATION OF PHOSPHATASE DEGRADER

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APP PUB NO 20240383908A1
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18577264

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Abstract

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A synthesis and an application of a phosphatase degrader are provided. The phosphatase degrader is a compound represented by formula I, or a salt thereof, or a deuterated compound thereof, or a stereoisomer thereof, or a solvate thereof, or a hydrate thereof, or a prodrug thereof. The compound can be used as a phosphatase degrader, especially as an SHP2 protein degrader, can treat malignant diseases such as tumors, and has good application prospects.

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Patent Owner(s)

Patent OwnerAddress
HINOVA PHARMACEUTICALS INCNO 2-3 4TH FLOOR RONGYAO TOWER 1 5 SOUTH KEYUAN ROAD CHENGDU 610041

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
AI, Chaowu Chengdu, Sichuan, CN 5 1
CHEN, Yuanwei Chengdu, Sichuan, CN 44 541
DU, Jing Chengdu, Sichuan, CN 41 133
FAN, Lei Chengdu, Sichuan, CN 48 298
HUO, Yongxu Chengdu, Sichuan, CN 6 1
LI, Xinghai Chengdu, Sichuan, CN 47 254
LIU, Chengcheng Chengdu, Sichuan, CN 19 43
LIU, Xingtai Chengdu, Sichuan, CN 1 0
LUO, Tongchuan Chengdu, Sichuan, CN 5 1
PENG, Shiming Chengdu, Sichuan, CN 7 8
PENG, Ying Chengdu, Sichuan, CN 81 559
TAN, Bin Chengdu, Sichuan, CN 73 435
WANG, Fei Chengdu, Sichuan, CN 1116 10607
XIAO, Daibiao Chengdu, Sichuan, CN 2 0
XU, Kexin Chengdu, Sichuan, CN 40 395
YU, Hua Chengdu, Sichuan, CN 126 889

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