A MICROBIAL ELECTROCHEMICAL TECHNOLOGY TO DETECT AND DEGRADE ORGANOPHOSPHATE PESTICIDES
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United States of America
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Nov 7, 2024
app pub date -
Sep 14, 2022
filing date -
Sep 14, 2022
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Abstract
Provided herein are recombinant microbial cells displaying on their surface a non-native protein capable of degrading an organophosphate, wherein the recombinant microbial cell has inhibited replication, as well as recombinant microbial cells engineered to be capable of expressing a non-native transcription factor that activates a non-native promoter in response to an organophosphate degradation product, wherein the non-native promoter is operatively linked to a nucleic acid encoding a reporter protein, wherein activity of the reporter protein can be detected, and their use for degrading organophosphates and detecting organophosphate degradation products.
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