MICROFLUIDIC DEVICE FOR MANUFACTURING BIOSCAFFOLD AND USE THEREOF
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United States of America
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Nov 7, 2024
app pub date -
Jan 25, 2023
filing date -
Jan 25, 2023
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Abstract
An aspect relates to a microfluidic device and use thereof. The microfluidic device of the present disclosure includes one or more micropillars therein, and thus, when the flow of blood is formed inside the device, shear stress is generated by the micropillars, leading to production of blood clots. The blood clots thus produced are vascularized and, when a wound site is treated therewith, simple wounds, viral infection caused by wounds, and chronic wounds can be significantly ameliorated. Blood vessels formed in the blood clots are aligned in the direction of blood flow so that a three-dimensional ECM structure suitable for tissues and organs can be manufactured.
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