STANDARD FOR GLYCOPROFILING OF PROTEINS
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United States of America
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Issued Date -
Oct 31, 2024
app pub date -
Aug 5, 2022
filing date -
Aug 5, 2022
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Abstract
The present invention relates to a method of relativizing signals by using a neoglycoprotein as a standard for glyco-proteins, wherein said neoglycoprotein comprises a streptavidin molecule bound through biotin to at least one pre-defined glycan determinant which comprises said glycan structure (A) and a corresponding use of said neoglycoprotein. Thereby, statements whether a particular glycan structure (A) is present on a protein of interest are possible. Applications in diagnosis of diseases such as cancer, autoimmune disease or inflammatory disease are disclosed.
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