TARGETED AND SLOW-RELEASE DRUG CONJUGATE COMPOSITION
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United States of America
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Oct 31, 2024
app pub date -
Mar 6, 2024
filing date -
Mar 6, 2024
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Abstract
The present invention introduces drug-loaded vehicles conjugated with aptamers, comprising DNA, RNA, or modified nucleic acid sequences designed to selectively and strongly bind to specific target sites on the eye, as well as binding to an ocular device such as a contact lens. Additionally, this innovative approach offers a targeted and sustained drug delivery method, addressing issues such as burst release of drugs, poor affinity between drug and material, and non-targeted drug delivery, while maintaining non-invasiveness and convenience.
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