INHIBITORS OF CANCER INVASION, ATTACHMENT, AND/OR METASTASIS
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United States of America
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Issued Date -
Oct 31, 2024
app pub date -
Dec 12, 2023
filing date -
Dec 12, 2023
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Abstract
Provided herein are, inter alia, compositions that bind to a PDZI domain of MDA-9/Syntenin (syndecan binding protein: SDCBP), thereby inhibiting MDA-9/Syntenin activity, and methods of use of same. The compositions and methods provided herein are useful for treating cancer and preventing cancer metastasis, particularly in cancers that have increased MDA-9/Syntenin expression.
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