ANTIBODY DRUG FOR PREVENTION OR TREATMENT OF AUTOIMMUNE DISEASES
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United States of America Patent
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Issued Date -
Oct 24, 2024
app pub date -
Aug 24, 2022
filing date -
Aug 24, 2022
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Abstract
The present invention relates to a selective immunomodulatory target antibody drug composition for prevention or treatment of autoimmune diseases. An anti-vimentin antibody of the present invention has the effects of inhibiting synovial tissue destruction and cartilage damage in rheumatoid arthritis and in intractable rheumatoid arthritis caused by obesity, specifically binding to both vimentin protein in serum and joint tissues and citrullinated vimentin protein and blocking same, and inhibiting etiological immune cells and thus the antibody can be effectively used for preventing or treating autoimmune diseases including rheumatoid arthritis.
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