BCMA CHIMERIC ANTIGEN RECEPTORS AND USES THEREOF

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United States of America Patent

APP PUB NO 20240350543A1
SERIAL NO

18638229

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ATTORNEY / AGENT: (SPONSORED)

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Abstract

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The present application provides BCMA targeting chimeric antigen receptor (CAR) comprising a BCMA binding region and an intracellular costimulatory domain derived from DAP10. Further provided are engineered immune effector cells (such as NK cells) comprising the chimeric antigen receptors. Pharmaceutical compositions, kits and methods of treating cancer are also provided.

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Patent Owner(s)

Patent OwnerAddress
TAKEDA DEVELOPMENT CENTER AMERICAS INC95 HAYDEN AVENUE LEXINGTON MA 02421

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Inventor(s)

Inventor Name Address # of filed Patents Total Citations
Basar, Rafet Houston, US 22 8
Curley, Michael David Cambridge, US 1 0
Lin, Paul Houston, US 186 3609
Meador,, III James Wilson Cambridge, US 1 0
Rezvani, Katy Houston, US 49 22
Talarico, LeeAnn Cambridge, US 4 11
Vishwanath, Prashanth Cambridge, US 18 92

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